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Mapping the green biosynthesis of silver nanoparticles: a bibliometric and patentometric analysis of scientific production and technological evolution
Conceição, Pietro Carlos Gonçalves, author.; de Assunção, Leonardo Moreira, author.; Araújo, Laíse Andrade Neves, author.; Mota, Zenilda de Jesus, author.; Pessoa, Clariane Teixeira, author.; Assis, Denilson de Jesus, author.; da Silva, Jania Betania Alves, author.; de Souza, Carolina Oliveira, author.; Cardoso, Lucas Guimarães, author.
2026
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Cite
Title
Mapping the green biosynthesis of silver nanoparticles: a bibliometric and patentometric analysis of scientific production and technological evolution
Author
Conceição, Pietro Carlos Gonçalves, author.
de Assunção, Leonardo Moreira, author.
Araújo, Laíse Andrade Neves, author.
Mota, Zenilda de Jesus, author.
Pessoa, Clariane Teixeira, author.
Assis, Denilson de Jesus, author.
da Silva, Jania Betania Alves, author.
de Souza, Carolina Oliveira, author.
Cardoso, Lucas Guimarães, author.
de Assunção, Leonardo Moreira, author.
Araújo, Laíse Andrade Neves, author.
Mota, Zenilda de Jesus, author.
Pessoa, Clariane Teixeira, author.
Assis, Denilson de Jesus, author.
da Silva, Jania Betania Alves, author.
de Souza, Carolina Oliveira, author.
Cardoso, Lucas Guimarães, author.
Item Type
Journal article
Description
1 volume.
Summary
The biosynthesis of silver nanoparticles (AgNPs) has emerged as a sustainable alternative to conventional physicochemical routes, employing renewable biological sources and reducing toxic agents. This study conducts a large-scale technological and scientific prospection of green AgNP synthesis, based on 373 patent families and 12,529 scientific articles indexed up to 2025. S-curve modeling indicates that scientific production maintains active growth (K = 18,000; r = 0.30), approaching 1600 annual publications in 2025, while patent filings enter technological consolidation (K = 440; r = 0.32). In articles, plant extract-based routes predominate (73%), with diverse phenolic compounds as reducing agents, notably Azadirachta indica (9%) and Ocimum sanctum (5%). In patents, more standardizable sources prevail, such as microorganisms (22%), isolated biomolecules, and hybrid systems (17%), with emphasis on Fusarium oxysporum (9%) and Bacillus subtilis (9%). China represented the leading patent publication jurisdiction (60%; CAGR = 18.2%), while India concentrated scientific production (CAGR = 30.5%). Universities represented 59% of applicants. Synthesis parameters converge to consolidated ranges: pH 6.0-10, Ag+ concentration 1-3 mM, and diameter 10-100 nm. Articles employ longer reaction times (1-24 h, 59%) with advanced techniques, whereas patents prioritize accelerated kinetics (<1 h, 57%) and integrated routes. The results evidence a field in transition, with academic experimentation paving the way for industrial consolidation.
Source of Description
Crossref
Series
World Patent Information ; 86, September, 2026
In
World Patent Information
Linked Resources
Published
Oxford [England] : Elsevier Ltd., 2026.
Language
English
Copyright Information
https://www.sciencedirect.com/science/article/abs/pii/S0172219023000108
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